Breck received his BS in Biology from the University of Wisconsin-Milwaukee and a PhD in Microbiology from the University of Washington in the laboratory of E. Peter Greenberg. He completed postdoctoral training in the laboratory of Lora Hooper at the University of Texas Southwestern Medical Center. Breck joined the faculty in the Department of Immunology and Microbiology at the University of Colorado – Anschutz Medical Campus in 2017. His lab studies mobile genetic elements including phages, conjugative plasmids, and transposons at the interfaces of host-microbe interactions, antibiotic resistance, and the microbiome. He has specialized in the study of phage-bacteria interactions of multidrug resistant enterococci. Using molecular genetics, animal models of colonization, and computational genomics, his group has revealed key insights into how phages influence enterococcal genome evolution, antiphage defenses, and environmental adaptation. These insights will help to inform the directions of phage therapies of the coming decade.